I used to shoot a .243 win. In a 700 rem. Now I built a 7mm rem mag in the same action, I have killed 4 antelope with it and a deer. A little overkill for antelope but it's loaded down. I chose this caliber because it can handle pretty much all big game I am interested in. Elk, deer, antelope. Sheep, and goat. And excellent qualities for long range hunting.
25-06 is probably the best round in my opinion if you took elk out of the picture not that it wouldn't do the job just maybe not as well.