I will have to vote for the 300 Win Mag. I have a 7mm mag I really love too. But if I was hunting something like grizzly I'd move up to my 338 Win....though I have no doubt my 300 Win Mag would be adquate. I have nothing against the 270 Win and 243 Win, I have killed a lot of game with them, it's just that they don't handle wind deflection well.