Isnt the .280 a necked down 30-06? I always thought the .280 was pretty comparable to the .270, just a slightly bigger bullet? I really like the .270 WSM and if I didnt have my trusty .270 Win and I were looking for a new gun I would seriously consider it. I think meat damage has alot more to do with shot placement then the caliber. Any caliber will do alot of damage if it hits in the wrong place. Not that many of these places wont pile an animal up dead in their tracks with 1 shot but there will be alot more damage then a double lung shot.