Only in 45 Colt, and on bears. Worked Great!!!! 300 Gr Deep Curl, 23.5gr H110. I have no idea how fast it is going but damn it hits hard. I have always used 300gr XTP's but I can't find them anymore, so I found 6 boxes of these and like them so far. I am sure you were asking for rifle applications but I hope this helps.
I've always used H4831 in my .270 Win: 60 grains with 130 grain bullets & 58 grains with 150 grain bullets. This year I am going to try IMR 4350 with 130 grain Partitions. I seem to get better accuracy with IMR powder.