Both are quality bullets with the Nosler being the better of the 2 IMO. I prefer the Barnes TTSX or a Nosler Accubond, Barnes will hold together better but the Accubond will do well also. I know Barnes recently came out with a 30. Caliber 180 grain TTSX as I purchased some for my 300 Weatherby. Also make sure whatever bullet you go with shoots well in your rifle as that's the most important factor. Good luck on whatever you choose.